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Best places to buy Kaspersky Anti-Virus in 2020 - Android CentralBest places to buy Kaspersky Anti-Virus in 2020 - Android CentralAntivirus Software Market Pin-Point Analyses of Industry Competition Dynamics to Offer You a Competitive Edge - 3rd Watch NewsAntivirus Software Market Research with Covid-19 after Effects - Apsters NewsAntivirus Software Market Scope by Trends, Opportunities to Expand Significantly by 2026 - Jewish Life NewsBest places to buy Kaspersky Anti-Virus in 2020 - Android CentralPosted: 28 Apr 2020 12:00 AM PDTKaspersky Anti-Virus is one of the best computer protection programs around, and has been thoroughly tested by several third-party labs and in our own in-house tests, too. The best place to purchase a copy of Kaspersky Anti-Virus is from Kaspersky itself. However, you can often find deals through other vendors. The trick is finding a trustworthy one, so you don't accidentally purchase and download malware instead of a legitimate copy of Kaspersky. Here a…

Genetically modified bacteria-killing viruses used on patient for first time - The San Diego Union-Tribune

Genetically modified bacteria-killing viruses used on patient for first time - The San Diego Union-Tribune


Genetically modified bacteria-killing viruses used on patient for first time - The San Diego Union-Tribune

Posted: 08 May 2019 12:00 AM PDT

Genetically engineered phages -- viruses that kill bacteria -- have been used for the first time to treat a patient struggling with a dangerous, persistent superbug infection.

The 15-year-old female patient had been infected with Mycobacterium abscessus, which is in the same genus as the bacterium that causes tuberculosis.

Researchers screened a database of more than 10,000 phages to find those active against the bacterium. They engineered three phages to make them more lethal.

The patient improved after treatment with the phage "cocktail," according to a study published Wednesday in Nature Medicine. It's online at j.mp/gephages.

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It is "plausible" that the modified phages were responsible, the study said. But making a firm conclusion wasn't possible, because only one patient was treated.

The treatment was modeled after the phage therapy given to UC San Diego professor Tom Patterson, who recovered after nearly being killed by his antibiotic-resistant infection. He got his phages from AmpliPhi, a San Diego biotech developing phage therapy; the U.S. Navy; and Texas A&M University.

Robert T. Schooley, a physician at UCSD who treated Patterson, was a study co-author.

Experts not involved with the study said the results represent an advance in phage therapy. That's because it was the first use of genetically engineered phages, and the first time phages were used against this kind of bacteria.

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Moreover, there is some evidence to suggest the treatment was effective, said Christine Schneider, a virologist at Carroll University in Wisconsin.

"In this type of study it is never possible to completely get at causation vs. correlation," Schneider said by email. "As they state, however, the timing of the improvements did not correlate with changes in other treatments the patient was receiving and they do have some data that suggests the phages they added replicated in the patient."

The study is "fantastic," phage specialist Dr. Benjamin Chan of Yale University said by email.

"Well designed and nicely executed,"Chan said. "It certainly advances the field and contributes to a growing body of research suggesting that phage therapy could be applied in diverse infections."

Derrick Fouts, a phage expert at the J. Craig Venter Institute in Rockville, Md., said finding the right combination of phages is tricky.

"One of the challenges that we face include being able to design phages that will work with any patient," Fouts said by email. "This is because phages tend to be specific to one or a few strains of bacteria and people can be infected with different strains. So, a phage designed for bacteria in one person may not work in another."

For engineered phages, another obstacle is getting the phages to "boot up," that is, to replicate inside the bacteria and package their genome inside the newly produced phages.

"My team of researchers at JCVI in Rockville are working on new methods to overcome this boot-up obstacle for engineering of phages for the treatment of wound infections," Fouts said.

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Anyone getting phage therapy is likely to be very seriously ill. This patient's condition was particularly precarious because a double-lung transplant had recently been performed to treat cystic fibrosis. In addition, the patient had diabetes, liver damage, and infection with Epstein-Barr virus.

As the infection progressed, the patient developed more skin lesions and the infection spread inside.

"Over 8 weeks, 20 additional skin nodules appeared on arms, legs, and buttocks, and the surgical wound showed areas of breakdown," the study said.

A team led by biologist Graham Hatfull of the University of Pittsburgh, and Dr. Helen Spencer at Great Ormond Street Hospital in London, searched through the SEA-PHAGES database, compiled by students at the University of Pittsburgh.

They found three candidate phages in soil-dwelling mycobacteria that don't infect people.

The phages infected Mycobacterium abscessus, but tended to live as permanent parasites.

Researchers took out a gene that allowed the phage to insert itself into the bacterial genome, said Dr. Schooley, the UCSD physician who treated Patterson. That turned the parasite into a killer, Schooley said.

The phages were introduced into the patient's abdomen and also given intravenously. Over a six-month period, the lesions gradually reduced, but didn't disappear.

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"It is plausible that phage resistance is associated with reduced virulence," the study said.

Patterson said he's still recovering, but "feeling great."

"This new case is very exciting and gratifying," Patterson said. "For me, all of the time and pain and suffering that I went through, is made worthwhile by the lives that are being saved by phage therapy."

Trade In Your Bulky Desktop For A Slim PC Or Chromebook That’s On Sale - The Daily Caller

Posted: 18 Jul 2019 12:00 AM PDT

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Samsung Chromebook 11.6″ 16GB (Refurbished)

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The Samsung Chromebook runs Chrome OS, perfect for surfing the Web, checking email, and video chatting right out the box. The ultra-light laptop easily fits in your bag so you can work and play anywhere. Use the 16GB hard drive to store all your files in one place. With a 1366 x 768 display, look at photos and watch videos in crisp color.

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AP Exclusive: Barr names new U.S. attorney in DC - The San Diego Union-Tribune

Posted: 30 Jan 2020 12:00 AM PST

Attorney General William Barr on Thursday named Timothy Shea, one of his closest advisers, to be the next top prosecutor in the nation's capital.

Shea will lead the largest U.S. attorney's office in the country, which has been historically responsible for some of the most significant and politically sensitive cases the Justice Department brings in the U.S.

He is a senior counselor to the attorney general and was Barr's right-hand man helping institute reforms at the federal Bureau of Prisons after Jeffrey Epstein's death at the Metropolitan Correctional Center in New York City.

As the U.S. attorney in the District of Columbia, Shea would oversee some of the lingering cases from special counsel Robert Mueller's Russia investigation, along with a number of politically charged investigations. The office is also generally responsible for handling potential prosecutions if Congress finds a witness in contempt.

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"Tim brings to this role extensive knowledge and expertise in law enforcement matters as well as an unwavering dedication to public service, reflected in his long and distinguished career in state and federal government," Barr said in a statement. "His reputation as a fair prosecutor, skillful litigator, and excellent manager is second-to-none, and his commitment to fighting violent crime and the drug epidemic will greatly benefit the city of Washington."

Prosecutors from the U.S. attorney's office had been investigating former FBI Deputy Director Andrew McCabe, a frequent target of President Donald Trump's wrath, and the prospect of charges seemed likely in the fall after his lawyers failed to persuade senior Justice Department officials that he didn't intentionally lie to internal investigators. Little has been said about the case in recent months.

The position generally requires Senate confirmation, but the law also allows federal judges to vote to appoint a U.S. attorney after a 120-day window. That was the case with Geoffrey Berman, the U.S. attorney in Manhattan.

Shea, a Boston-area native who comes from a family of first responders, is widely seen as being able to bridge a gap between law enforcement officials and the community, especially in Washington. The office is unique because its 300 or so prosecutors have jurisdiction to prosecute both local and federal crimes in the nation's capital.

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"He's the definitive public servant," said Jim Pasco, the executive director of the National Fraternal Order of Police. "He has a real reverence for the law and a real dedication to making communities safer."

Shea has served in a variety of roles in the Justice Department from working as a line prosecutor to being associate deputy attorney general. As an assistant U.S. attorney, he prosecuted violent crimes, fraud, public corruption and drug trafficking cases and he's also led a task force that was responsible for investigating and prosecuting prison crimes and had also worked as a congressional staffer in the House and Senate.

He was the chief counsel and staff director for the U.S. Senate Permanent Subcommittee on Investigations, which was chaired at the time by Sen. Susan Collins, a Maine Republican, and also worked on the staff of the House Appropriations Committee.

Collins said in a statement that Shea "did an outstanding job leading in-depth investigations into issues ranging from consumer protection to government waste, fraud, and abuse."

"With his decades of legal experience in both the private and public sectors, Tim has a wealth of knowledge that will serve him well in his new role," she added.

In the wake of Epstein's death, Barr and Shea worked hand-in-hand to manage the crisis and investigation into the circumstances surrounding the wealthy financier's death. Shea visited the jail days after Epstein's suicide and helped advise the attorney general as Barr shook up the agency's leadership, removing its acting director.

Shea, who begins his new role on Feb. 3, replaces Jessie Liu, who has been nominated to become the undersecretary for terrorism and financial crimes at the Treasury Department, as the Trump administration imposes economic sanctions as a national security tool. The attorney general said Liu had "served with distinction" as U.S. attorney.

Barr had nominated Liu to become the associate attorney general, the third-highest job in the department, overseeing civil litigation, but she withdrew from consideration after encountering opposition on the Republican-led Senate Judiciary Committee because of her past membership in a lawyers' group that has supported abortion rights.

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Liu would be first U.S. attorney to assume the role at Treasury. When she was U.S. attorney, her office brought several sanctions-related cases and issued a warrant to seize an Iranian supertanker caught in a diplomatic standoff because of violations of U.S. sanctions, money laundering and terrorism statutes.

US says Chinese military stole masses of Americans' data - The San Diego Union-Tribune

Posted: 10 Feb 2020 12:00 AM PST

Four members of the Chinese military have been charged with breaking into the computer networks of the Equifax credit reporting agency and stealing the personal information of tens of millions of Americans, the Justice Department said Monday, blaming Beijing for one of the largest hacks in history to target consumer data.

The hackers in the 2017 breach stole the personal information of roughly 145 million Americans, collecting names, addresses, Social Security and driver's license numbers and other data stored in the company's databases. The intrusion damaged the company's reputation and underscored China's increasingly aggressive and sophisticated intelligence-gathering methods.

"The scale of the theft was staggering," Attorney General William Barr said Monday in announcing the indictment. "This theft not only caused significant financial damage to Equifax, but invaded the privacy of many millions of Americans, and imposed substantial costs and burdens on them as they have had to take measures to protect against identity theft."

The case is the latest U.S. accusation against Chinese hackers suspected of breaching networks of American corporations, including steel manufacturers, a hotel chain and a health insurer. It comes as the Trump administration has warned against what it sees as the growing political and economic influence of China, and efforts by Beijing to collect data for financial and intelligence purposes and to steal research and innovation.

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The indictment arrives at a delicate time in relations between Washington and Beijing. Even as President Donald Trump points to a preliminary trade pact with China as evidence of his ability to work with the Communist government, other members of his administration have been warning against cybersecurity and surveillance risks posed by China, especially as the tech giant Huawei seeks to become part of new, high-speed 5G wireless networks across the globe.

Experts and U.S. officials say the Equifax theft is consistent with the Chinese government's interest in accumulating as much information about Americans as possible.

The data can be used by China to target U.S. government officials and ordinary citizens, including possible spies, and to find weaknesses and vulnerabilities that can be exploited — such as for purposes of blackmail. The FBI has not seen that happen yet in this case, said Deputy Director David Bowdich, though he said it "doesn't mean it will or will not happen in the future."

"We have to be able to recognize that as a counterintelligence issue, not a cyber issue," Bill Evanina, the U.S. government's top counterintelligence official, said of the Equifax case.

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The four accused hackers are suspected members of the People's Liberation Army, an arm of the Chinese military that was blamed in 2014 for a series of intrusions into American corporations.

Prosecutors say they exploited a software vulnerability to gain access to Equifax's computers, obtaining log-in credentials that they used to navigate databases and review records. They also took steps to cover their tracks, the indictment says, wiping log files on a daily basis and routing traffic through about three dozen servers in nearly 20 countries.

Besides stealing personal information, the hackers also made off with some of the company's sensitive trade secrets, including database designs, law enforcement officials said.

Equifax, headquartered in Atlanta, maintains a massive repository of consumer information that it sells to businesses looking to verify identities or assess creditworthiness. All told, the indictment says, the company holds information on hundreds of millions of people in America and abroad.

None of the accused hackers is in U.S. custody. But officials nonetheless hope criminal charges can be a deterrent to foreign hackers and a warning to other countries that American law enforcement has the capability to pinpoint individual culprits. Even so, while China and the U.S. committed in 2015 to halt acts of cyber espionage against each other, the Equifax intrusion and others like it make clear that Beijing has continued its operations.

A spokesperson for the Chinese Embassy in Washington did not return an email seeking comment Monday.

The case resembles a 2014 indictment that accused five members of the PLA of hacking into American corporations to steal trade secrets. U.S. authorities also suspect China in the 2015 breach of the federal Office of Personnel Management and of intrusions into the Marriott hotel chain and health insurer Anthem.

Such hacks "seem to deliberately cast a wide net" so that Chinese intelligence analysts can get deep insight into the lives of Americans, said Ben Buchanan, a Georgetown University scholar and author of the upcoming book "The Hacker and the State."

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"This could be especially useful for counterintelligence purposes, like tracking American spies posted to Beijing," Buchanan said.

Barr, who at an event last week warned of Beijing's aspirations of economic dominance, said Monday the U.S. has long "witnessed China's voracious appetite for the personal data of Americans."

"This kind of attack on American industry is of a piece with other Chinese illegal acquisitions of sensitive personal data," Barr said.

The criminal charges, which include conspiracy to commit computer fraud and conspiracy to commit economic espionage, were filed in federal court in Atlanta.

Equifax last year reached a $700 million settlement over the data breach, with the bulk of the funds intended for consumers affected by it.

Equifax officials told the Government Accountability Office the company made many mistakes, including having an outdated list of computer systems administrators. The company didn't notice the intruders targeting its databases for more than six weeks. Hackers exploited a known security vulnerability that Equifax hadn't fixed.

While company stock has recovered, Equifax's reputation has not fully. The company was dragged in front of Congress no less than four times to explain what happened.

The company is about to start paying out claims on its $700 million settlement, of which more claimants have opted in to getting a cash settlement than accept credit counseling. So many claims have been made for the cash that the lawyers suing Equifax and the Federal Trade Commission have warned claimants that the chance of getting the full cash value of the settlement was unlikely.

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Associated Press writers Nick Jesdanun and Ken Sweet in New York and Frank Bajak in Boston contributed to this report.

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